論文

欧文（原著論文・総説）

Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates. Okada M, Kawagoe Y, Sato Y, Nozumi M, Ishikawa Y, Tamada A, Yamazaki H, Sekino Y, Kanemura Y, Shinmyo Y, Kawasaki H, Kaneko N, Sawamoto K, Fujii Y, Igarashi M. Mol Brain. 2021 Apr 8;14(1):66. doi: 10.1186/s13041-021-00755-0. PMID: 33832520 

Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone in mice. Ito N, Riyadh MA, Ahmad SAI, Hattori S, Kanemura Y, Kiyonari H, Abe T, Furuta Y, Shinmyo Y, Kaneko N, Hirota Y, Lupo G, Hatakeyama J, Abdulhaleem M FA, Anam MB, Yamaguchi M, Takeo T, Takebayashi H, Takebayashi M, Oike Y, Nakagata N, Shimamura K, Holtzman MJ, Takahashi Y, Guillemot F, Miyakawa T, Sawamoto K, Ohta K. Sci Transl Med. 2021 Mar 31;13(587):eaay7896. doi: 10.1126/scitranslmed.aay7896. PMID: 33790026

Metabolic fingerprints of fear memory consolidation during sleep. Koyanagi I, Sonomura K, Naoi T, Ohnishi T, Kaneko N, Sawamoto K, Sato TA, Sakaguchi M. Mol Brain. 2021 Feb 10;14(1):30. doi: 10.1186/s13041-021-00733-6. PMID: 33568175 

Effects of interferon-alpha on hippocampal neurogenesis and behavior in common marmosets. Kaneko N*, Nakamura S, Sawamoto K* (*corresponding author).. Mol Brain. 2020 Jun 26;13(1):98. doi: 10.1186/s13041-020-00639-9. PMID: 32590991 

Neurogenesis and neuronal migration in the postnatal ventricular-subventricular zone: Similarities and dissimilarities between rodents and primates. Akter M, Kaneko N, Sawamoto K. Neurosci Res. 2021 Jun;167:64-69. doi: 10.1016/j.neures.2020.06.001. Epub 2020 Jun 15. PMID: 32553727 Review.

Sparse Activity of Hippocampal Adult-Born Neurons during REM Sleep Is Necessary for Memory Consolidation. Kumar D, Koyanagi I, Carrier-Ruiz A, Vergara P, Srinivasan S, Sugaya Y, Kasuya M, Yu TS, Vogt KE, Muratani M, Ohnishi T, Singh S, Teixeira CM, Chérasse Y, Naoi T, Wang SH, Nondhalee P, Osman BAH, Kaneko N, Sawamoto K, Kernie SG, Sakurai T, McHugh TJ, Kano M, Yanagisawa M, Sakaguchi M. Neuron. 2020 Aug 5;107(3):552-565.e10. doi: 10.1016/j.neuron.2020.05.008. Epub 2020 Jun 4. PMID: 32502462 

Dynamic Changes in the Neurogenic Potential in the Ventricular-Subventricular Zone of Common Marmoset during Postnatal Brain Development. Akter M#, Kaneko N#*, Herranz-Pérez V, Nakamura S, Oishi H, García-Verdugo JM, Sawamoto K* (#equal contribution, *corresponding author). Cereb Cortex. 2020 Jun 1;30(7):4092-4109. doi: 10.1093/cercor/bhaa031. PMID: 32108222

Dynamic Changes in Ultrastructure of the Primary Cilium in Migrating Neuroblasts in the Postnatal Brain. Matsumoto M, Sawada M, García-González D, Herranz-Pérez V, Ogino T, Bang Nguyen H, Quynh Thai T, Narita K, Kumamoto N, Ugawa S, Saito Y, Takeda S, Kaneko N, Khodosevich K, Monyer H, García-Verdugo JM, Ohno N, Sawamoto K. J Neurosci. 2019 Dec 11;39(50):9967-9988. doi: 10.1523/JNEUROSCI.1503-19.2019. Epub 2019 Nov 4. PMID: 31685650 

Blood vessels as a scaffold for neuronal migration. Fujioka T, Kaneko N, Sawamoto K. Neurochem Int. 2019 Jun;126:69-73. doi: 10.1016/j.neuint.2019.03.001. Epub 2019 Mar 6. PMID: 30851365 Review.

New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration. Kaneko N, Herranz-Pérez V, Otsuka T, Sano H, Ohno N, Omata T, Nguyen HB, Thai TQ, Nambu A, Kawaguchi Y, García-Verdugo JM, Sawamoto K. Sci Adv. 2018 Dec 12;4(12):eaav0618. doi: 10.1126/sciadv.aav0618. eCollection 2018 Dec. PMID: 30547091 

Ventricular-subventricular zone fractones are speckled basement membranes that function as a neural stem cell niche. Sato Y, Kiyozumi D, Futaki S, Nakano I, Shimono C, Kaneko N, Ikawa M, Okabe M, Sawamoto K, Sekiguchi K. Mol Biol Cell. 2019 Jan 1;30(1):56-68. doi: 10.1091/mbc.E18-05-0286. Epub 2018 Oct 31. PMID: 30379609 

Shootin1b Mediates a Mechanical Clutch to Produce Force for Neuronal Migration. Minegishi T, Uesugi Y, Kaneko N, Yoshida W, Sawamoto K, Inagaki N. Cell Rep. 2018 Oct 16;25(3):624-639.e6. doi: 10.1016/j.celrep.2018.09.068. PMID: 30332643 

Go with the Flow: Cerebrospinal Fluid Flow Regulates Neural Stem Cell Proliferation. Kaneko N, Sawamoto K. Cell Stem Cell. 2018 Jun 1;22(6):783-784. doi: 10.1016/j.stem.2018.05.015. PMID: 29859165 

Detachment of Chain-Forming Neuroblasts by Fyn-Mediated Control of cell-cell Adhesion in the Postnatal Brain. Fujikake K, Sawada M, Hikita T, Seto Y, Kaneko N, Herranz-Pérez V, Dohi N, Homma N, Osaga S, Yanagawa Y, Akaike T, García-Verdugo JM, Hattori M, Sobue K, Sawamoto K. J Neurosci. 2018 May 9;38(19):4598-4609. doi: 10.1523/JNEUROSCI.1960-17.2018. Epub 2018 Apr 16. PMID: 29661967 

Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury. Jinnou H, Sawada M, Kawase K, Kaneko N, Herranz-Pérez V, Miyamoto T, Kawaue T, Miyata T, Tabata Y, Akaike T, García-Verdugo JM, Ajioka I, Saitoh S, Sawamoto K. Cell Stem Cell. 2018 Jan 4;22(1):128-137.e9. doi: 10.1016/j.stem.2017.11.005. Epub 2017 Dec 21. PMID: 29276142 

Unique Organization of the Nuclear Envelope in the Post-natal Quiescent Neural Stem Cells. Cebrián-Silla A, Alfaro-Cervelló C, Herranz-Pérez V, Kaneko N, Park DH, Sawamoto K, Alvarez-Buylla A, Lim DA, García-Verdugo JM. Stem Cell Reports. 2017 Jul 11;9(1):203-216. doi: 10.1016/j.stemcr.2017.05.024. Epub 2017 Jun 22. PMID: 28648897 

Affinity-Immobilization of VEGF on Laminin Porous Sponge Enhances Angiogenesis in the Ischemic Brain. Oshikawa M, Okada K, Kaneko N, Sawamoto K, Ajioka I. Adv Healthc Mater. 2017 Jun;6(11). doi: 10.1002/adhm.201700183. Epub 2017 May 10. PMID: 28488337

Mechanisms of neuronal migration in the adult brain. Kaneko N, Sawada M, Sawamoto K. J Neurochem. 2017 Jun;141(6):835-847. doi: 10.1111/jnc.14002. Epub 2017 Apr 9. PMID: 28251650 

β1 integrin signaling promotes neuronal migration along vascular scaffolds in the post-stroke brain. Fujioka T, Kaneko N, Ajioka I, Nakaguchi K, Omata T, Ohba H, Fässler R, García-Verdugo JM, Sekiguchi K, Matsukawa N, Sawamoto K. EBioMedicine. 2017 Feb;16:195-203. doi: 10.1016/j.ebiom.2017.01.005. Epub 2017 Jan 9. PMID: 28153772 

Genome-Wide Association Study Identifies ZNF354C Variants Associated with Depression from Interferon-Based Therapy for Chronic Hepatitis C. Matsunami K, Nishida N, Kaneko N, Ikeo K, Toyo-Oka L, Takeuchi H, Matsuura K, Tamori A, Nomura H, Yoshiji H, Imamura M, Masaki N, Hayakawa T, Ide T, Shimada N, Ikeda F, Hino K, Nishiguchi S, Okuse C, Nojiri S, Sawamoto K, Tokunaga K, Joh T, Tanaka Y. PLoS One. 2016 Oct 10;11(10):e0164418. doi: 10.1371/journal.pone.0164418. eCollection 2016. PMID: 27723809 

Characterization of multiciliated ependymal cells that emerge in the neurogenic niche of the aged zebrafish brain. Ogino T, Sawada M, Takase H, Nakai C, Herranz-Pérez V, Cebrián-Silla A, Kaneko N, García-Verdugo JM, Sawamoto K. J Comp Neurol. 2016 Oct 15;524(15):2982-92. doi: 10.1002/cne.24001. Epub 2016 Apr 4. PMID: 26991819

Minocycline treatment ameliorates interferon-alpha- induced neurogenic defects and depression-like behaviors in mice. Zheng LS, Kaneko N*, Sawamoto K* (*corresponding author). Front Cell Neurosci. 2015 Jan 28;9:5. doi: 10.3389/fncel.2015.00005. eCollection 2015. PMID: 25674053 

Mechanisms for interferon-α-induced depression and neural stem cell dysfunction. Zheng LS#, Hitoshi S#, Kaneko N#*, Takao K, Miyakawa T, Tanaka Y, Xia H, Kalinke U, Kudo K, Kanba S, Ikenaka K, Sawamoto K* (#equal contribution, *corresponding author). Stem Cell Reports. 2014 Jun 26;3(1):73-84. doi: 10.1016/j.stemcr.2014.05.015. eCollection 2014 Jul 8. PMID: 25068123 

Enhancement of ventricular-subventricular zone-derived neurogenesis and oligodendrogenesis by erythropoietin and its derivatives. Kaneko N, Kako E, Sawamoto K. Front Cell Neurosci. 2013 Nov 27;7:235. doi: 10.3389/fncel.2013.00235. PMID: 24348331 

Human dental pulp-derived stem cells protect against hypoxic-ischemic brain injury in neonatal mice. Yamagata M, Yamamoto A, Kako E, Kaneko N, Matsubara K, Sakai K, Sawamoto K, Ueda M. Stroke. 2013 Feb;44(2):551-4. doi: 10.1161/STROKEAHA.112.676759. Epub 2012 Dec 13. PMID: 23238858

A subtype-specific critical period for neurogenesis in the postnatal development of mouse olfactory glomeruli. Kato Y#, Kaneko N#, Sawada M#, Ito K, Arakawa S, Murakami S, Sawamoto K (#equal contribution). PLoS One. 2012;7(11):e48431. doi: 10.1371/journal.pone.0048431. Epub 2012 Nov 1. PMID: 23133633 

Growth factors released from gelatin hydrogel microspheres increase new neurons in the adult mouse brain. Nakaguchi K, Jinnou H, Kaneko N, Sawada M, Hikita T, Saitoh S, Tabata Y, Sawamoto K. Stem Cells Int. 2012;2012:915160. doi: 10.1155/2012/915160. Epub 2012 Oct 10. PMID: 23093979 

Subventricular zone-derived oligodendrogenesis in injured neonatal white matter in mice enhanced by a nonerythropoietic erythropoietin derivative. Kako E, Kaneko N, Aoyama M, Hida H, Takebayashi H, Ikenaka K, Asai K, Togari H, Sobue K, Sawamoto K. Stem Cells. 2012 Oct;30(10):2234-47. doi: 10.1002/stem.1202. PMID: 22890889

A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors. Shinohara R, Thumkeo D, Kamijo H, Kaneko N, Sawamoto K, Watanabe K, Takebayashi H, Kiyonari H, Ishizaki T, Furuyashiki T, Narumiya S. Nat Neurosci. 2012 Jan 15;15(3):373-80, S1-2. doi: 10.1038/nn.3020. PMID: 22246438 

Sensory input regulates spatial and subtype-specific patterns of neuronal turnover in the adult olfactory bulb. Sawada M, Kaneko N, Inada H, Wake H, Kato Y, Yanagawa Y, Kobayashi K, Nemoto T, Nabekura J, Sawamoto K. J Neurosci. 2011 Aug 10;31(32):11587-96. doi: 10.1523/JNEUROSCI.0614-11.2011. PMID: 21832189 

Strategies for regenerating striatal neurons in the adult brain by using endogenous neural stem cells. Nakaguchi K, Masuda H, Kaneko N, Sawamoto K. Neurol Res Int. 2011;2011:898012. doi: 10.1155/2011/898012. Epub 2011 Jun 2. PMID: 21766028 

Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain. Wang Y#, Kaneko N#, Asai N#, Enomoto A, Isotani-Sakakibara M, Kato T, Asai M, Murakumo Y, Ota H, Hikita T, Namba T, Kuroda K, Kaibuchi K, Ming GL, Song H, Sawamoto K, Takahashi M (#equal contribution). J Neurosci. 2011 Jun 1;31(22):8109-22. doi: 10.1523/JNEUROSCI.1130-11.2011. PMID: 21632933 

Prospects and limitations of using endogenous neural stem cells for brain regeneration. Kaneko N, Kako E, Sawamoto K. Genes (Basel). 2011 Jan 14;2(1):107-30. doi: 10.3390/genes2010107. PMID: 24710140 

New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Kaneko N, Marín O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K. Neuron. 2010 Jul 29;67(2):213-23. doi: 10.1016/j.neuron.2010.06.018. PMID: 20670830 

Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia. Oki K, Kaneko N, Kanki H, Imai T, Suzuki N, Sawamoto K, Okano H. Neurosci Res. 2010 Apr;66(4):390-5. doi: 10.1016/j.neures.2009.12.013. Epub 2009 Dec 28. PMID: 20036290

Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Enomoto A, Asai N, Namba T, Wang Y, Kato T, Tanaka M, Tatsumi H, Taya S, Tsuboi D, Kuroda K, Kaneko N, Sawamoto K, Miyamoto R, Jijiwa M, Murakumo Y, Sokabe M, Seki T, Kaibuchi K, Takahashi M. Neuron. 2009 Sep 24;63(6):774-87. doi: 10.1016/j.neuron.2009.08.015. PMID: 19778507 

Adult neurogenesis and its alteration under pathological conditions. Kaneko N, Sawamoto K. Neurosci Res. 2009 Mar;63(3):155-64. doi: 10.1016/j.neures.2008.12.001. Epub 2008 Dec 11. PMID: 19118585 Review.

Cyclin-dependent kinase 5 is required for control of neuroblast migration in the postnatal subventricular zone. Hirota Y, Ohshima T, Kaneko N, Ikeda M, Iwasato T, Kulkarni AB, Mikoshiba K, Okano H, Sawamoto K. J Neurosci. 2007 Nov 21;27(47):12829-38. doi: 10.1523/JNEUROSCI.1014-07.2007. PMID: 18032654 

Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb. Kaneko N, Okano H, Sawamoto K. Genes Cells. 2006 Oct;11(10):1145-59. doi: 10.1111/j.1365-2443.2006.01010.x. PMID: 16999735 

Suppression of cell proliferation by interferon-alpha through interleukin-1 production in adult rat dentate gyrus. Kaneko N, Kudo K, Mabuchi T, Takemoto K, Fujimaki K, Wati H, Iguchi H, Tezuka H, Kanba S. Neuropsychopharmacology. 2006 Dec;31(12):2619-26. doi: 10.1038/sj.npp.1301137. Epub 2006 Jul 5. PMID: 16823390

和文（総説・著書）

金子奈穂子. 脳梗塞後のニューロン再生過程の解析. (日本神経化学会優秀賞受賞者研究紹介) 神経化学 Vol.58 No.2, 69-78 (2019) http://neurochem-j.jp/10.11481/topics108/data/index.html

岩田英敏, 金子奈穂子, 大塚隆信, 澤本和延. 脳梗塞に対する内在性神経幹細胞活性化を用いた治療. Clinical Neuroscience 34巻11号 46-49 中外医学社 (2016)　

金子奈穂子. ニューロンの移動と反応性アストロサイト. ブレインサイエンス・レビュー 2016: 195-212 (2016)

金子奈穂子, 澤本和延. 脳室下帯. 脳科学事典. 日本神経科学学会脳科学辞典編集委員会 (2015) https://bsd.neuroinf.jp/wiki/脳室下帯

金子奈穂子, 澤本和延. 成体ニューロン新生. 再生医療用語ハンドブック 領域：脳・神経／責任編集者：岡野栄之 p 164-165,　日本再生医療学会監修　メディカルトリビューンISBN: 978-4-89589-478-4 (2015)

金子奈穂子. 成体脳内で産生され長距離を移動する新生ニューロンとアストロサイトの相互作用. 神経化学 50: 29-37 (2011)

金子奈穂子. グリア細胞との相互作用による新生ニューロンの移動制御機構. 再生医療 10: 45-51 (2011)

金子奈穂子, 澤本和延. 成体脳を移動する新生ニューロンは周囲のアストロサイトの形態制御によって自らの移動経路を形成・維持している. ライフサイエンス新着論文レビュー（2010）https://first.lifesciencedb.jp/archives/882

金子奈穂子, 澤本和延. 成体脳におけるニューロン新生と脳梗塞後の神経新生メカニズム. 実験医学 増刊 神経回路の制御と脳機能発現のメカニズム 26: 224-229 (2008)

金子奈穂子, 澤本和延. 成体脳のニューロン新生とその異常. Brain and Nerve 60: 319-328 (2008)

藤井千太, 金子奈穂子, 橘川博江, 佐々木裕光, 永井宏, 石井久敬, 西村良二, 黒木俊秀, 中村純, 白川治, 前田潔, 渡邊衡一郎, 中込和幸, 神庭重信, 新福尚隆. 日本における抗うつ薬処方の現状 アジア5ケ国における国際共同処方調査. 日本社会精神医学会雑誌14巻1号: 30-35（2005）

金子奈穂子, 塩江邦彦, 神庭重信. 双極Ⅰ型障害. 精神医学症候群Ⅰ、融 道男 編、日本臨牀社: 251-255（2003）

井口博登, 金子奈穂子, 神庭重信. 双極性障害の経過と予後. 双極性障害の治療スタンダード. 樋口輝彦, 神庭重信 編. 星和書店: 137-146（2002）